Intra-arterial infusion of leptin does not affect blood pressure in salt-loaded rabbits     

Mohammad MA  Talafih K  Mohamad MM  Khabaz MN 《Pakistan journal of biological sciences: PJBS》2010,13(15):761-764

The aim of this research is to see the effect of intra-arterial infusion of leptin on blood pressure of salt loaded rabbits in vivo. Increased blood pressure was produced in rabbits by giving diets containing 8% sodium chloride for 5 weeks. Leptin in different concentrations was infused intra-arterially into rabbits fed on high salt diets and the response was compared in rabbits fed with low salt diets. High salt diets produced significant increase in blood pressure. In rabbits fed with low salt diet, leptin infused intra-arterially caused an increase in blood pressure while infusion of leptin into rabbits fed with high salt diets does not affect the blood pressure. In conclusion, salt loading to rabbits abolishes the effect ofleptin on cardiovascular system. This may indicate that leptin effect on sympathetic activity is altered by high salt diets in these animals.  相似文献   

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice     

M.R. Sulaiman  E.K. Perimal  M.N. Akhtar  A.S. Mohamad  M.H. Khalid  N.A. Tasrip  F. Mokhtar  Z.A. Zakaria  N.H. Lajis  D.A. Israf 《Fitoterapia》2010

The anti-inflammatory activity of zerumbone (1), a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith was investigated using carrageenan-induced paw edema and cotton pellet-induced granuloma tissue formation test in mice. It was demonstrated that intraperitoneal administration of 1 at a dose of 5, 10, 50 and 100 mg/kg produced significant dose-dependent inhibition of paw edema induced by carrageenan. It was also demonstrated that 1 at similar doses significantly suppressed granulomatous tissue formation in cotton pellet-induced granuloma test.  相似文献   

Treatability of Methylene Blue Solution by Adsorption Process Using Neobalanocarpus hepmii and Capsicum annuum     

Risky Ayu Kristanti  Mohamad Khairul Ariffin Kamisan  Tony Hadibarata 《Water, air, and soil pollution》2016,227(5):134

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Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrus Merr     

Chan KY  Mohamad K  Ooi AJ  Imiyabir Z  Chung LY 《Fitoterapia》2012,83(5):961-967

Lipoxygenase (LOX)-inhibiting compounds from the leaves of Chisocheton polyandrus Merr. were isolated in this study using a bioactivity-guided fractionation technique. Two dammarane triterpenoids, dammara-20,24-dien-3-one (1) (IC(50)=0.69±0.07 μM) and 24-hydroxydammara-20,25-dien-3-one (2) (IC(50)=1.11±0.38 μM), were isolated and identified based on the soybean LOX assay. Dammara-20,24-dien-3-one (1) exhibited dual inhibition of both human 5-LOX (IC(50)=24.27±2.92 μM) and cyclooxygenase-2 (COX-2) (IC(50)=3.17±0.90 μM), whereas 24-hydroxydammara-20,25-dien-3-one (2) did not exhibit any significant inhibitory effects. This report is the first to detail the inhibition of LOX and COX by both C. polyandrus and its isolated compounds.  相似文献   

The origin of Indonesian cattle and conservation genetics of the Bali cattle breed     

Mohamad K  Olsson M  Andersson G  Purwantara B  van Tol HT  Rodriguez-Martinez H  Colenbrander B  Lenstra JA 《Reproduction in domestic animals》2012,47(Z1):18-20

Both Bos indicus (zebu) and Bos javanicus (banteng) contribute to the Indonesian indigenous livestock, which is supposedly of a mixed species origin, not by direct breeding but by secondary cross-breeding. Here, the analysis of mitochondrial, Y-chromosomal and microsatellite DNA showed banteng introgression of 10-16% in Indonesian zebu breeds with East-Javanese Madura and Galekan cattle having higher levels of autosomal banteng introgression (20-30%) and combine a zebu paternal lineage with a predominant (Madura) or even complete (Galekan) maternal banteng origin. Two Madura bulls carried taurine Y-chromosomal haplotypes, presumably of French Limousin origin. There was no evidence for zebu introgression in five populations of the Bali cattle, a domestic form of the banteng.  相似文献   

Review on Labisia pumila (Kacip Fatimah): Bioactive phytochemicals and skin collagen synthesis promoting herb     

Lee Suan Chua  Sze Yean LeeNorhanisah Abdullah  Mohamad Roji Sarmidi 《Fitoterapia》2012

Labisia pumila is a traditional herb widely used as post-partum medication for centuries. Recently, extensive researches have been carried out on the phytochemical identification, biological and toxicological studies for the herb. Phytochemicals found in the herbal extract showed high antioxidant properties, which were essential for various pharmacological activities. The significant findings are anti-estrogenic deficiency and -immunodeficiency diseases. Another finding that has considerable impact on natural product research is the contribution of L. pumila in promoting skin collagen synthesis. The performance of the herb as anti-aging agent due to natural aging process and accelerated by UV radiation was reviewed critically.  相似文献   

Ovine and caprine toxoplasmosis (Toxoplasma gondii) in aborted animals in Jordanian goat and sheep flocks     

Abu-Dalbouh MA  Ababneh MM  Giadinis ND  Lafi SQ 《Tropical animal health and production》2012,44(1):49-54

Two hundred and fifty-five biological samples (106 aborted foetal tissue samples and 149 blood samples from aborted sheep and goats) were collected from 188 animals during the lambing season from September 2009 to April 2010 from the Mafraq region of Jordan. The sampled animals belonged to 93 goat and sheep flocks that had cases of abortion. A total of 169 (66.3%) biological samples were collected from sheep and 86 (33.7%) from goats. Seventy-six (29.8%) biological samples (45 blood and 31 tissue samples) were positive for Toxoplasma gondii by PCR assay. The positive samples were obtained from 43 sheep and 23 goats. The overall toxoplasma-specific prevalence rate was 35.1% (66/188). Forty flocks (43%) had at least one T. gondii PCR-positive animal. The risk factors related to flock health status and farm management that are hypothesized to be associated with T. gondii PCR positivity were also assessed using multiple logistic regressions. The presence of cats (OR = 4.74), a large flock size (OR = 2.76) and the method of disposing the aborted foetuses (OR = 3.77) were all statistically significant (P < 0.05) risk factors that were positively associated with toxoplasma positivity in goat and sheep flocks.  相似文献   

Assessment of Compost Extract on Yield and Phytochemical Contents of Pak Choi (Brassica rapa cv. chinensis) Grown under Different Fertilizer Strategies     

Abd Rahman Jabir Mohd Din  Kian Kai Cheng  Mohamad Roji Sarmidi 《Communications in Soil Science and Plant Analysis》2017,48(3):274-284

An experiment was conducted to assess the effect of different extraction of compost extracts on pak choi (Brassica rapa cv. chinensis) under two fertilizer regimes. Aerated compost extract (ACE) and non-aerated compost extract (NCE) were prepared and all treatments (ACE + organic fertilizer, NCE + organic fertilizer, ACE + inorganic fertilizer, NCE + inorganic fertilizer) were conducted in randomized block design. Soil microbiological analysis after treatment was done. Plants grown with ACE + inorganic fertilizers yielded maximum in fresh, dry weight, and N mineral content compared to others. Plants receiving NCE + organic fertilizers produced a higher phenolic content, whereas antioxidant capacity was observed maximum at NCE + inorganic fertilizers. Soil microbiological analysis significantly increased in yeast and nitrogen fixing bacteria count at ACE + organic fertilizers. The co-application of inorganic fertilizers and compost extract had a significant effect on vegetative growth, quality of the pak choi, and soil fertility.  相似文献   

Enhanced mechanical and thermal properties of hybrid graphene nanoplatelets/multiwall carbon nanotubes reinforced polyethylene terephthalate nanocomposites     

I.?M.?Inuwa  Reza?Arjmandi  Akos?Noel?Ibrahim  M.?K.?Mohamad?Haafiz  S.?L.?Wong  Khaliq?Majeed  Azman?HassanEmail author 《Fibers and Polymers》2016,17(10):1657-1666

The effects of graphene nanoplatelets (GNP) and multiwall carbon nanotube (MWCNT) hybrid nanofillers on the mechanical and thermal properties of reinforced polyethylene terephthalate (PET) have been investigated. The nanocomposites were melt blended using the counter rotating twin screw extruder followed by injection molding. Their morphology, mechanical and thermal properties were characterized. Combination of the two nanofillers in composites formulation supplemented each other which resulted in the overall improvement in adhesion between fillers and matrix. The mechanical properties and thermal stability of the hybrid nanocomposites (PET/GNP1.5/MWCNT1.5) were significantly improved compared to PET/GNP3 and PET/MWCNT3 single filer nanocomposites. However, it was observed that GNP was better in improving the mechanical properties but MWCNT resulted in higher thermal stability of Nanocomposite. The transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) revealed uniform dispersion of the hybrid fillers in PET/GNP1.5/MWCNT1.5 nanocomposites while agglomeration was observed at higher filler content. The MWCNT prevented the phenomenal stacking of the GNPs by forming a bridge between adjacent GNP planes resulting in higher dispersion of fillers. This complimentary geometrical structure is responsible for the significant improvement in the thermal stability and mechanical properties of the hybrid nanocomposites.  相似文献   

The first reported artificial propagation of yellow puffer,Xenopterus naritus (Richardson, 1848) from Sarawak,Northwestern Borneo          下载免费PDF全文

Ahmad Syafiq Ahmad Nasir  Samsur Mohamad  Mohammed Mohidin 《Aquaculture Research》2017,48(8):4582-4589

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